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A Randomized Trial of Anticoagulants Vs Aspirin After Cerebral Ischemia of Presumed Arterial Origin SPIRIT Study Group, Ann Neurol 42:857-8651997., , 1997 See this aricle in Pubmed Article Abstract Aspirin is only modestly effective in the secondary prevention after cerebral ischemia.Studies in other vascular disorders suggest that anticoagulant drugs in patients with cerebral ischemia of presumed arterial(noncardiac)origin might be more effective.The aim of the Stroke Prevention in Reversible Ischemia Trial(SPIRIT)therefore was to compare the efficacy and safety of 30 mg aspirin daily and oral anticoagulation (inter-national normalized ratio[INR]3.0-4.5).Patient referred to a neurologist in one of 58 collaborating centers because of a transient ischemic attack or minor ischemic stroke(Rankin grade

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(click to filter results - removes previous filter) adverse drug reaction anticoagulant,complications of anticoagulant,treatment anticoagulant,treatment in CVD aspirin cerebral ischemia cerebrovascular accident cerebrovascular accident,prevention of coumarin INR values intracerebral hemorrhage intracranial hemorrhage prevention of neurologic disorders transient ischemic attack

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